Xiaofeng Wang

Professor

State Key Laboratory of Crop Stress Biology in Arid Areas  College of Horticulture, Northwest A&F University

No.3 Taicheng Road,

Yangling, Shaanxi Province, 712100, ChinaE-mail: wangxff99@nwsuaf.edu.cn

Education

07/1999    Ph.D., Plant Molecular Biology and Vegetable Physiology, Dissertation topic: Studies on genetic engineering of salt tolerance in  Brassica Oleracea  Var. Capitata and  B .  Napus .

07/1993    M.S., Crop Genetics and Breeding, Thesis: Genetic research of quantitative traits on oyster mushroom ( Pleurotus   O  streatus ).

07/1990  B.S., Horticulture,

All above degrees were earned in Northwestern University of Agriculture, P. R. China.

Professional Experience

2010--present   Professor, Northwest A & F University, Shaanxi, P. R. China

2007--2010     Research Associate, North Carolina State University, NC, USA.

2002--2007     Post doctor, North Carolina State University, NC, USA.

2000--2002     Post doctor, Agricultural Research Organization of Israel (Volcani Center) and Weizmann Institute of Science, Israel

1999-2000     Associate Professor, Northwestern University of Agriculture, P. R. China

1993-1999    Assistant Professor, Northwestern University of Agriculture, P. R. China

Academic Interests

Brassinosteroids (BRs) are plant steroid hormones that regulate a wide range of developmental and physiological processes. I am interested in the signal transduction pathways through which BRs regulate plant growth and development. To gain a comprehensive understanding of the molecular mechanism of BRs signal transduction pathways and to provide inter-disciplinary training to students, a wide spectrum of approaches, including plant tissue culture,  genetic transformation, gene clones, molecular genetics, biochemistry, proteomics, and cell biology, have been applied. Furthermore, a large effort has been dedicated to molecular breedings of horticultural crops with the latest discoveries in molecular mechanism of BRs signal transduction pathway.

Courses

The main courses have been taught:,, < Cultivation Science of Vegetables>, < Cultivation Science of Edible fungi>,, < General Vegetable Gardening >,et al.

Honors and Awards

Honored with ‘Hundred of Excellent Experts in Shaanxi Province”

Selected Publications

1. Jianwei Liu, Shufen Wang, Hao Wang, Bote Luo, Yiyong Cai, Xiaodong Li, Yanfeng Zhang*, Xiaofeng Wang*. (2021) Rapid generation of tomato male-sterile lines with a marker use for hybrid seed production by CRISPR/Cas9 system. Molecular Breeding. 41:25. doi:10.1007/s11032-021-01215-2.

2. Shuhua Huang, Yuxiu Liu, Rui Deng, Tiantian Lei, Aijuan Tian, Haihua Ren, Shufen Wang, Xiaofeng Wang*. (2021) Genome-wide identification and expression analysis of the GSK gene family in  Solanum tuberosum  L. under abiotic stress and phytohormone treatments and functional characterization of StSK21 involvement in salt stress. Gene. 766:145156.

3. Shufen Wang, Tixu Hu, Aijuan Tian, Bote Luo, Chenxi Du, Siwei Zhang, Shuhua Huang,  Fei Zhang，Xiaofeng Wang*. (2020) Modification of serine 1040 of SIBRI1 increases fruit yield by enhancing tolerance to heat stress in tomato. International Journal of molecular Sciences. 21(20):7681. doi:10.3390/ijms21207681.

4. Yong Yang, Jun Liu, Chuanchun Yin, Luciano de Souza Vespoli, Dongdong Ge, Yanyan Huang, Baomin Feng, Guangyuan Xu, Ana Marcia E. de A. Manhães, Shijuan Dou, Cameron Criswell, Libo Shan, Xiaofeng Wang, Ping He*. (2020) RNAi-based screen reveals concerted functions of MEKK2 and CRCK3 in plant cell death regulation. Plant Physiology. 183(1):331-344. doi: 10.1104/pp.19.01555.

5. Shan Zhang, Cheng Li, Haihua Ren, Tong Zhao, Qi Li, Shufen Wang, Yanfeng Zhang, Fangming Xiao*, Xiaofeng Wang*（2020）BAK1 mediates light intensity to phosphorylate and activate catalases to regulate plant growth and development. International Journal of Molecular Sciences. 21(4):1437. doi: 10.3390/ijms21041437.

6. Shufen Wang, Jianwei Liu, Tong Zhao, Chenxi Du, Shuming Nie, Yanfeng Zhang, Siqi Lv, Shuhua Huang, Xiaofeng Wang*. (2019) Modification of threonine-1050 of SlBRI1 regulates BR signalling and increases fruit yield of tomato. BMC Plant Biology. 19(1):256. doi: 10.1186/s12870-019-1869-9.

7. Shuming Nie, Shuhua Huang, Shufen Wang, Yujiao Mao, Jianwei Liu, Ruili Ma, Xiaofeng Wang*. (2019) Enhanced brassinosteroid signaling intensity via SlBRI1 overexpression negatively regulates drought resistance in a manner opposite of that via exogenous BR application in tomato. Plant Physiology and Biochemistry. 138:36-47. doi: 10.1016/j.plaphy.2019.02.014.

8. Yanfeng Zhang, Shuhua Huang, Xuefang Wang, Jianwei Liu, Xupeng Guo, Jianxin Mu*, Jianhua Tian, Xiaofeng Wang*. (2018) Defective APETALA2 genes lead to sepal modification in Brassica crops. Frontiers in Plant Science, 9:367. doi: 10.3389/fpls.2018.00367

9. Imkampe J, Halter T, Huang S, Schulze S, Mazzotta S, Schmidt N, Manstretta R, Postel S, Wierzba M, Yang Y2, vanDongen WM, Stahl M, Zipfel C, Goshe MB, Clouse S, de Vries SC, Tax F, Wang X*, Kemmerling B* . (2017) The arabidopsis leucine-rich repeat receptor kinase BIR3 negatively regulates BAK1 receptor complex formation and stabilizes BAK1. The Plant Cell. 9: 2285-2303. doi: 10.1105/tpc.17.00376.

10. Shuhua Huang, Shuming Nie, Shufen Wang, Jianwei Liu, Yanfeng Zhang, Xiaofeng Wang*. (2017) SlBIR3 negatively regulates PAMP responses and cell death in tomato. International Journal of Molecular Sciences.18(9):1966. doi: 10.3390/ijms18091966.

11. Shuming Nie, Shuhua Huang, Shufen Wang, Dandan Cheng, Jianwei Liu, Siqi Lv, Qi Li, Xiaofeng Wang*. (2017) Enhancing brassinosteroid signaling via overexpression of tomato ( Solanum lycopersicum )  SlBRI1  improves major agronomic traits. Frontiers in Plant Science. 8:1386. doi: 10.3389/fpls.2017.01386.

12. Cheng Li, Shan Zhang, Xiaofeng Wang*. (2017) Novel signaling interface constituted with membrane receptor-like kinases emerged from the study of interaction and transphosphorylation of BRI1 and BAK1. Current Topics in Medicinal Chemistry．17(21):2393-2400. doi: 10.2174/1568026617666170414144145.

13. Qiannan Wang, Shufen Wang, Sufu Gan, Xin Wang, Jianwei Liu, Xiaofeng Wang*. (2016) Role of specific phosphorylation sites of Arabidopsis brassinosteroid-insensitive 1 receptor kinase in plant growth and development. Journal of Plant Growth Regulation. 35(3): 755-769. DOI 10.1007/s00344-016-9580-7

14. Xin Wang, Dongli Gao, Jinjing Sun, Min Liu, YaoYao Lun, Jianshu Zheng, Shenhao Wang, Qingzhi Cui, Xiaofeng Wang*, Sanwen Huang*. (2016) An exon skipping in a SEPALLATA-Like gene is associated with perturbed floral and fruits development in cucumber. Journal of Integrative Plant Biology. 58(9):766-771. doi: 10.1111/jipb.12472.

15. Shan Zhang, Cheng Li, Qi Li, Qiannan Wang, Shuhua Huang, Yanfeng Zhang and Xiaofeng Wang*. (2015) Functional divergence of BAK1 genes from  Brassica rapa  in regulating plant architecture. Genetics and Molecular Research. 14 (4): 14587-14596

16. Srijeet K. Mitra, Ruiqiang Chen, Murali Dhandaydham, Xiaofeng Wang, Kevin R. Blackburn, Uma Kota, Michael B. Goshe, Daniel Schwartz, Steven C. Huber, Steven D. Clouse*. (2015) An autophosphorylation site database for leucine-rich repeat receptor-like kinases in  Arabidopsis thaliana . Plant Journal:82(6):1042-60.

17. Vikramjit S. Bajwa, Xiaofeng Wang, Kevin R. Blackburn, Michael B. Goshe, Srijeet K. Mitra, Elisabeth L. Williams, Gerard J. Bishop, Sergei Krasnyanski, George Allen, Steven C. Huber, and Steven D. Clouse*. (2013) Identification and functional analysis of tomato BRI1 and BAK1 receptor kinase phosphorylation sites. Plant Physiology: 163 (1):30-42.

18. Man-Ho Oh, Xiaofeng Wang, Steven D. Clouse, and Steven C. Huber*. (2012) Deactivation of the Arabidopsis BRI1 receptor kinase by autophosphorylation within the glycine-rich loop involved in ATP binding. Proc Natl Acad Sci U S A, 109(1):327-332.

19. Man-Ho Oh, Xiaofeng Wang, Uma Kota, Michael B. Goshe, Steven D. Clouse, and Steven C. Huber*. (2009) Tyrosine phosphorylation of the BRI1 receptor kinase emerges as a component of Brassinosteroid signaling in Arabidopsis. Proc Natl Acad Sci U S A, 106 (2):658-663

20. Xiaofeng Wang, Uma Kota, Kai He, Kevin Blackburn, Jia Li, Michael B. Goshe, Steven C. Huber, Steven D. Clouse*. (2008) Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in Brassinosteroid signaling. Developmental Cell, 15(2):220-235

21. Xiaofeng Wang, Michael B. Goshe, Erik J. Soderblom, Brett S. Phinney, Jason A. Kuchar, Jia Li, Tadao Asami, Shigeo Yoshida, Steven C. Huber, Steven D. Clouse*. (2005) Identification and functional analysis of  in vivo  phosphorylation sites of the Arabidopsis BRASSINOSTEROID INSENSITIVE 1 receptor kinase. The Plant Cell, 17: 1685-1170

22. Lianhai Fu, Xiaofeng Wang, Yoram Eyal, Yimin She, Lynda J. Donald, Kenneth G. Standing, Gozal Ben-Hayyim*. (2002) A selenoprotein in the plant kingdom: mass spectrometry confirms that an opal codon (UGA) encodes selenocysteine in  Chamydomonas reinhadtii  glutathion peroxidase. Journal of Biological Chemistry, 277(29):25983-25991