1. 基本信息
李宝华，男，1978年1月出生，教授，博士生导师
2. 教育经历
2001.09-2008.07，中国科学院遗传发育所，植物分子遗传学专业，博士
1996.09-2000.07，北京理工大学，生物化学工程专业，学士
3. 工作经历
2019.09至今，西北农林科技大学园艺学院，教授
2009.07-2019.08，加州大学戴维斯分校，博士后、助理项目科学家
4. 研究方向
十字花科蔬菜次生代谢产物生物合成的转录调控机理
十字花科蔬菜功能基因组学
十字花科蔬菜种质资源创制
5. 科研项目
西北农林科技大学引进人才科研启动项目，主持（2019-2024）
国家自然基金面上项目（32070333），主持（2021-2024）
6. 研究论文（#共第一作者，*通讯作者）
~2019年9月至今：
Chen L, Li C, Zhang J, Li Z, Zeng Q, Sun Q, Wang X, Zhao L, Zhang L, Li B* (2024) Transcriptome analysis reveals core drought-responsive genes and dynamics of abscisic acid pathways in Chinese cabbage (Brassica rapa). Journal of Integrative Agriculture (Accepted)
Chen L#, Zeng Q#, Zhang J, Li C, Bai X, Sun F, Kliebenstein DJ*, Li B* (2024) Large-scale identification of novel transcriptional regulators of the aliphatic glucosinolate pathway in Arabidopsis. Journal of experimental botany 75: 300-315
Zhang R, Yang W, Pan Q, Zeng Q, Yan C, Bai X, Liu Y, Zhang L, Li B* (2023) Effects of long-term blue light irradiation on carotenoid biosynthesis and antioxidant activities in Chinese cabbage (Brassica rapa L. ssp. pekinensis). Food research international 174: 113661
Zhang R, Liu Y, Pan Q, Khan A, Bai X, Ali M, Yang W, Zhang L*, Li B* (2023) The effects of short term blue light treatment on promoting nutrition value in Chinese cabbage. Food Chem 412: 135542
Zhang R, Zhang N, Wang Y, Khan A, Ma S, Bai X, Zeng Q, Pan Q, Li B*, Zhang L* (2023) Blue light induces leaf color change by modulating carotenoid metabolites in orange-head Chinese cabbage (Brassica rapa L.ssp. pekinensis). Journal of Integrative Agriculture 22
Pan Q, Zhang J, Yan C, Khan A, Fei S, Lei T, Xu Z, Li B, Zhang R*, Hui M* (2023) Distribution of Indolic Glucosinolates in Different Developmental Stages and Tissues of 13 Varieties of Cabbage (Brassica oleracea L. var. capitata). Horticulturae 9
Hummel NFC, Zhou A, Li B, Markel K, Ornelas IJ, Shih PM*(2023) The trans-regulatory landscape of gene networks in plants. Cell systems 14: 501-511 e504
Zhang R, Zhang J, Li C, Pan Q, Haq SU, Mosa WFA, Fang F, Zhang L, Li B* (2023) The Accumulation of Health-Promoting Nutrients from Representative Organs across Multiple Developmental Stages in Orange Chinese Cabbage. Plants 12
DeWolf E*, Brock MT, Calder WJ, Kliebenstein DJ, Katz E, Li B, Morrison HG, Maignien L, Weinig C (2023) The rhizosphere microbiome and host plant glucosinolates exhibit feedback cycles in Brassica rapa. Molecular ecology 32: 741-751
Sun Q, Xu Z, Huang W, Li D, Zeng Q, Chen L, Li B*, Zhang E* (2022) Integrated metabolome and transcriptome analysis reveals salicylic acid and flavonoid pathways' key roles in cabbage's defense responses to Xanthomonas campestris pv. campestris. Frontiers in plant science 13: 1005764
Chen L, Shen Y, Yang W, Pan Q, Li C, Sun Q, Zeng Q, Li B*, Zhang L* (2022) Comparative Metabolic Study of Two Contrasting Chinese Cabbage Genotypes under Mild and Severe Drought Stress. International journal of molecular sciences 23
Cibils-Stewart X*, Kliebenstein DJ, Li B, Giles K, McCornack BP, Nechols J (2022) Aphid Species and Feeding Location on Canola Influences the Impact of Glucosinolates on a Native Lady Beetle Predator. Environmental entomology 51: 52-62
Tang M#, Li B#, Zhou X, Bolt T, Li JJ, Cruz N, Gaudinier A, Ngo R, Clark-Wiest C, Kliebenstein DJ*, Brady SM* (2021) A genome-scale TF-DNA interaction network of transcriptional regulation of Arabidopsis primary and specialized metabolism. Molecular systems biology 17: e10625
Ruiz KA, Pelletier JM, Wang Y, Feng MJ, Behr JS, Ethao TQ, Li B, Kliebenstein D, Harada JJ, Jenik PD* (2021) A reevaluation of the role of the ASIL trihelix transcription factors as repressors of the seed maturation program. Plant direct 5: e345
Garrido AN, Supijono E, Boshara P, Douglas SJ, Stronghill PE, Li B, Nambara E, Kliebenstein DJ, Riggs CD* (2020) flasher, a novel mutation in a glucosinolate modifying enzyme, conditions changes in plant architecture and hormone homeostasis. The Plant journal : for cell and molecular biology 103: 1989-2006
Fernandez-Calvo P, Inigo S, Glauser G, Vanden Bossche R, Tang M, Li B, De Clercq R, Nagels Durand A, Eeckhout D, Gevaert K, De Jaeger G, Brady SM, Kliebenstein DJ, Pauwels L, Goossens A*, Ritter A (2020) FRS7 and FRS12 recruit NINJA to regulate expression of glucosinolate biosynthesis genes. The New phytologist 227: 1124-1137
Li B#, Tang M#, Caseys C#, Nelson A, Zhou M, Zhou X, Brady SM, Kliebenstein DJ* (2020) Epistatic Transcription Factor Networks Differentially Modulate Arabidopsis Growth and Defense. Genetics 214: 529-541
Salehin M, Li B, Tang M, Katz E, Song L, Ecker JR, Kliebenstein DJ, Estelle M* (2019) Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels. Nature communications 10: 4021
~2019年9月之前的代表性论文
Li B, Tang M, Nelson A, Caligagan H, Zhou X, Clark-Wiest C, Ngo R, Brady SM, Kliebenstein DJ* (2018) Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. The Plant cell 30: 178-195
Wang JZ#, Li B#, Xiao Y#, Ni Y, Ke H, Yang P, de Souza A, Bjornson M, He X, Shen Z, Balcke GU, Briggs SP, Tissier A, Kliebenstein DJ, Dehesh K* (2017) Initiation of ER Body Formation and Indole Glucosinolate Metabolism by the Plastidial Retrograde Signaling Metabolite, MEcPP. Molecular plant 10: 1400-1416
Jia W#, Li B#, Li S#, Liang Y, Wu X, Ma M, Wang J, Gao J, Cai Y, Zhang Y, Wang Y, Li J*, Wang Y* (2016) Mitogen-Activated Protein Kinase Cascade MKK7-MPK6 Plays Important Roles in Plant Development and Regulates Shoot Branching by Phosphorylating PIN1 in Arabidopsis. PLoS biology 14: e1002550
Zhang Y#, Li B#, Huai D, Zhou Y*, Kliebenstein DJ* (2015) The conserved transcription factors, MYB115 and MYB118, control expression of the newly evolved benzoyloxy glucosinolate pathway in Arabidopsis thaliana. Frontiers in plant science 6: 343
Li B, Kliebenstein DJ* (2014) The AT-hook motif-encoding gene METABOLIC NETWORK MODULATOR 1 underlies natural variation in Arabidopsis primary metabolism. Frontiers in plant science 5: 415
Li B, Gaudinier A, Tang M, Taylor-Teeples M, Nham NT, Ghaffari C, Benson DS, Steinmann M, Gray JA, Brady SM, Kliebenstein DJ* (2014) Promoter-based integration in plant defense regulation. Plant physiology 166: 1803-1820
7. 联系方式
通讯地址：陕西省西北农林科技大学园艺学院，邮编712100
电子邮箱：baohuali@nwafu.edu.cn
